Complex cardiac rhythms

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Cardiac Rhythms and Arrhythmias

node as the region responsible for activation of the heart.1 Laslett first suggested sinus node dysfunction as a cause of bradycardia in 1909, and during the 1950s and 1960s Short, Ferrer, Lown, and others described the clinical spectrum of sinus node dysfunction that is commonly called the “sick sinus syndrome resting sinus bradycardia.”2-5 Sinus node dysfunction can have multiple electrocardi...

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Spontaneous initiation and termination of complex rhythms in cardiac cell culture.

INTRODUCTION Complex cardiac arrhythmias often start and stop spontaneously. These poorly understood behaviors frequently are associated with pathologic modification of the structural heterogeneity and functional connectivity of the myocardium. To evaluate underlying mechanisms, we modify heterogeneity by varying the confluence of embryonic chick monolayer cultures that display complex bursting...

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Calcium and cardiac rhythms: physiological and pathophysiological.

Calcium plays two pivotal roles in cardiac excitationcontraction (E-C) coupling.1 Ca drives myofilament activation and carries or regulates ionic currents that are responsible for normal electrical rhythms2 as well as life-threatening arrhythmias.3 In this editorial, I will focus on Ca and pacemaker activity and arrhythmogenesis. Ca entry via Ca current (ICa) triggers sarcoplasmic reticulum (SR...

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A case of strange cardiac rhythms

A 60-year-old professor of astrophysics falls from a ladder while picking cherries from the tree. An ambulance is called to take him to the hospital. Initially, he is conscious but confused. While in the ambulance, he develops supraventricular and ventricular arrhythmias and then ventricular fibrillation. He is resuscitated but unfortunately aspirates during intubation. No history is obtainable...

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Ablnormal Cardiac Rhythms Caused by Acetyicholine

The effect of topical administration of acetylcholine on the auricular and ventricular surface of the dog's heart was studied. The experiments show the appearance of variform arrhv-thmias, particularly auricular fibrillation. The tendency for the development of these arrhvthmias is diminished but not abolished by atropinization. The experiments confirm previous results of the authors according ...

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ژورنال

عنوان ژورنال: Nature

سال: 1987

ISSN: 0028-0836,1476-4687

DOI: 10.1038/330695a0